Oxidative Stress Contributes to Lung Injury and Barrier Dysfunction via Microtubule Destabilization

Oxidative stress is an important part of host innate immune response to foreign pathogens, such as bacterial LPS, but excessive activation of redox signaling may lead to pathologic endothelial cell (EC) activation and barrier dysfunction. Microtubules (MTs) play an important role in agonist-induced...

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Главные авторы: Kratzer, Eric, Tian, Yufeng, Sarich, Nicolene, Wu, Tinghuai, Meliton, Angelo, Leff, Alan, Birukova, Anna A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2012
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547103/
https://ncbi.nlm.nih.gov/pubmed/22842495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0161OC
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