Oxidative Stress Contributes to Lung Injury and Barrier Dysfunction via Microtubule Destabilization

Oxidative stress is an important part of host innate immune response to foreign pathogens, such as bacterial LPS, but excessive activation of redox signaling may lead to pathologic endothelial cell (EC) activation and barrier dysfunction. Microtubules (MTs) play an important role in agonist-induced...

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Autores principales: Kratzer, Eric, Tian, Yufeng, Sarich, Nicolene, Wu, Tinghuai, Meliton, Angelo, Leff, Alan, Birukova, Anna A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2012
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547103/
https://ncbi.nlm.nih.gov/pubmed/22842495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0161OC
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