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Activation of the HIF Prolyl Hydroxylase by the Iron Chaperones PCBP1 and PCBP2
Mammalian cells express dozens of iron-containing proteins, yet little is known about the mechanism of metal ligand incorporation. Human poly (rC) binding protein 1 (PCBP1) is an iron chaperone that binds iron and delivers it to ferritin, a cytosolic iron storage protein. We have identified the iron...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361910/ https://ncbi.nlm.nih.gov/pubmed/22055506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.08.015 |
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