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Cyclin D1 inactivation extends proliferation and alters histogenesis in the postnatal mouse retina

BACKGROUND: The cell cycle regulator Cyclin D1 is expressed in embryonic retinal progenitor cells (RPCs) and regulates their cell cycle rate and neurogenic output. We report here that Cyclin D1 also has important functions in postnatal retinal histogenesis. RESULTS: The initial production of Müller...

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Main Authors: Das, Gaurav, Clark, Anna M., Levine, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361900/
https://ncbi.nlm.nih.gov/pubmed/22434780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.23782
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