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Vsx2 / Chx10 Ensures the Correct Timing and Magnitude of Hedgehog Signaling in the Mouse Retina
Vertebrate retinal progenitor cells (RPCs) undergo a robust proliferative expansion to produce enough cells for the retina to form appropriately. Vsx2 (formerly Chx10), a homeodomain protein expressed in RPCs, is required for sufficient proliferation to occur. Sonic Hedgehog protein (SHH), secreted...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671289/ https://ncbi.nlm.nih.gov/pubmed/18417110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.02.055 |
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