Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle

Cyclin-dependent kinases CDK4 and CDK6 are essential for the control of the cell cycle through the G(1) phase. Aberrant expression of CDK4 and CDK6 is a hallmark of cancer, which would suggest that CDK4 and CDK6 are attractive targets for cancer therapy. Herein, we report that calcein AM (the calcei...

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Detalhes bibliográficos
Main Authors: Zanuy, Miriam, Ramos-Montoya, Antonio, Villacañas, Oscar, Canela, Nuria, Miranda, Anibal, Aguilar, Esther, Agell, Neus, Bachs, Oriol, Rubio-Martinez, Jaime, Pujol, Maria Dolors, Lee, Wai-Nang P., Marin, Silvia, Cascante, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361763/
https://ncbi.nlm.nih.gov/pubmed/22661920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-011-0328-x
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