Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

[Image: see text] The hepatic organic anion transporting polypeptides (OATPs) influence the pharmacokinetics of several drug classes and are involved in many clinical drug–drug interactions. Predicting potential interactions with OATPs is, therefore, of value. Here, we developed in vitro and in sili...

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Hlavní autoři: Karlgren, Maria, Vildhede, Anna, Norinder, Ulf, Wisniewski, Jacek R., Kimoto, Emi, Lai, Yurong, Haglund, Ulf, Artursson, Per
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361267/
https://ncbi.nlm.nih.gov/pubmed/22541068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300212s
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