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Hexokinase Regulates Susceptibility to Bax-Mediated Mitochondrial Membrane Injury after Ischemic Stress
Hexokinase (HK), the rate-limiting enzyme in glycolysis, regulates cell survival either by promoting metabolism and/or inhibiting apoptosis. HKI and HKII, isoforms with mitochondrial targeting sequences, were studied in renal epithelial cells after ATP depletion, an insult that activates GSK3β and B...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361076/ https://ncbi.nlm.nih.gov/pubmed/21430642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.532 |
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