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High throughput structural analysis of yeast ribosomes using hSHAPE

Global mapping of rRNA structure by traditional methods is prohibitive in terms of time, labor and expense. High throughput selective 2′ hydroxyl acylation analyzed by primer extension (hSHAPE) bypasses these problems by using fluorescently labeled primers to perform primer extension reactions, the...

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Bibliographische Detailangaben
Hauptverfasser: Leshin, Jonathan A, Heselpoth, Ryan, Belew, Ashton Trey, Dinman, Jonathan D
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360075/
https://ncbi.nlm.nih.gov/pubmed/21508682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.3.14453
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