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High throughput structural analysis of yeast ribosomes using hSHAPE

Global mapping of rRNA structure by traditional methods is prohibitive in terms of time, labor and expense. High throughput selective 2′ hydroxyl acylation analyzed by primer extension (hSHAPE) bypasses these problems by using fluorescently labeled primers to perform primer extension reactions, the...

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Detalhes bibliográficos
Main Authors: Leshin, Jonathan A, Heselpoth, Ryan, Belew, Ashton Trey, Dinman, Jonathan D
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360075/
https://ncbi.nlm.nih.gov/pubmed/21508682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.8.3.14453
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