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Enantioselective Total Synthesis of (+)-Amabiline

[Image: see text] The first total synthesis of (+)-amabiline, an unsaturated pyrrolizidine alkaloid from Cynoglossum amabile is reported. This convergent, enantioselective synthesis proceeds in 15 steps, 10 steps longest linear sequence, in 6.2% overall yield and features novel methodology to constr...

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Autores principales: Senter, Timothy J., Fadeyi, Olugbeminiyi O., Lindsley, Craig W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359844/
https://ncbi.nlm.nih.gov/pubmed/22432912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300466a
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