Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate-activated protein kinase and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) signalling axis senses the metabolic dema...

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Détails bibliographiques
Auteurs principaux: Roy Chowdhury, Subir K., Smith, Darrell R., Saleh, Ali, Schapansky, Jason, Marquez, Alexandra, Gomes, Suzanne, Akude, Eli, Morrow, Dwane, Calcutt, Nigel A., Fernyhough, Paul
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359752/
https://ncbi.nlm.nih.gov/pubmed/22561641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws097
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