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Ciliary neurotrophic factor activates NF-κB to enhance mitochondrial bioenergetics and prevent neuropathy in sensory neurons of streptozotocin-induced diabetic rodents

Diabetes causes mitochondrial dysfunction in sensory neurons that may contribute to peripheral neuropathy. Ciliary neurotrophic factor (CNTF) promotes sensory neuron survival and axon regeneration and prevents axonal dwindling, nerve conduction deficits and thermal hypoalgesia in diabetic rats. In t...

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書誌詳細
主要な著者: Saleh, Ali, Roy Chowdhury, Subir K., Smith, Darrel R., Balakrishnan, Savitha, Tessler, Lori, Martens, Corina, Morrow, Dwane, Schartner, Emily, Frizzi, Katie E., Calcutt, Nigel A., Fernyhough, Paul
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521091/
https://ncbi.nlm.nih.gov/pubmed/23022047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.09.015
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