Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate-activated protein kinase and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) signalling axis senses the metabolic dema...

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Hauptverfasser: Roy Chowdhury, Subir K., Smith, Darrell R., Saleh, Ali, Schapansky, Jason, Marquez, Alexandra, Gomes, Suzanne, Akude, Eli, Morrow, Dwane, Calcutt, Nigel A., Fernyhough, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359752/
https://ncbi.nlm.nih.gov/pubmed/22561641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws097
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