Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

Mitochondrial dysfunction occurs in sensory neurons and may contribute to distal axonopathy in animal models of diabetic neuropathy. The adenosine monophosphate-activated protein kinase and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) signalling axis senses the metabolic dema...

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Main Authors: Roy Chowdhury, Subir K., Smith, Darrell R., Saleh, Ali, Schapansky, Jason, Marquez, Alexandra, Gomes, Suzanne, Akude, Eli, Morrow, Dwane, Calcutt, Nigel A., Fernyhough, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359752/
https://ncbi.nlm.nih.gov/pubmed/22561641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws097
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