Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment

OBJECTIVE: Impairments in mitochondrial physiology may play a role in diabetic sensory neuropathy. We tested the hypothesis that mitochondrial dysfunction in sensory neurons is due to abnormal mitochondrial respiratory function. RESEARCH DESIGN AND METHODS: Rates of oxygen consumption were measured...

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Main Authors: Chowdhury, Subir K. Roy, Zherebitskaya, Elena, Smith, Darrell R., Akude, Eli, Chattopadhyay, Sharmila, Jolivalt, Corinne G., Calcutt, Nigel A., Fernyhough, Paul
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844817/
https://ncbi.nlm.nih.gov/pubmed/20103706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1299
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