A Humanized Pattern of Aromatase Expression Is Associated with Mammary Hyperplasia in Mice

Aromatase is essential for estrogen production and is the target of aromatase inhibitors, the most effective endocrine treatment for postmenopausal breast cancer. Peripheral tissues in women, including the breast, express aromatase via alternative promoters. Female mice lack the promoters that drive...

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Detalhes bibliográficos
Main Authors: Zhao, Hong, Pearson, Elizabeth K., Brooks, David C., Coon V, John S., Chen, Dong, Demura, Masashi, Zhang, Ming, Clevenger, Charles V., Xu, Xia, Veenstra, Timothy D., Chatterton, Robert T., DeMayo, Francesco J., Bulun, Serdar E.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
General Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359608/
https://ncbi.nlm.nih.gov/pubmed/22508516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1761
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