A Humanized Pattern of Aromatase Expression Is Associated with Mammary Hyperplasia in Mice

Aromatase is essential for estrogen production and is the target of aromatase inhibitors, the most effective endocrine treatment for postmenopausal breast cancer. Peripheral tissues in women, including the breast, express aromatase via alternative promoters. Female mice lack the promoters that drive...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Zhao, Hong, Pearson, Elizabeth K., Brooks, David C., Coon V, John S., Chen, Dong, Demura, Masashi, Zhang, Ming, Clevenger, Charles V., Xu, Xia, Veenstra, Timothy D., Chatterton, Robert T., DeMayo, Francesco J., Bulun, Serdar E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
Soggetti:
General Endocrinology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359608/
https://ncbi.nlm.nih.gov/pubmed/22508516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1761
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi