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A Humanized Pattern of Aromatase Expression Is Associated with Mammary Hyperplasia in Mice
Aromatase is essential for estrogen production and is the target of aromatase inhibitors, the most effective endocrine treatment for postmenopausal breast cancer. Peripheral tissues in women, including the breast, express aromatase via alternative promoters. Female mice lack the promoters that drive...
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| Hlavní autoři: | , , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Endocrine Society
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359608/ https://ncbi.nlm.nih.gov/pubmed/22508516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1761 |
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