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Changes in Aromatase (CYP19) Gene Promoter Usage in Non-Small Cell Lung Cancer
In humans, aromatase (CYP19) gene expression is regulated via alternative promoters. Activation of each promoter gives rise to a CYP19 mRNA species with a unique 5′-untranslated region. Inhibition of aromatase has been reported to downregulate lung tumor growth. The genetic basis for CYP19 gene expr...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118270/ https://ncbi.nlm.nih.gov/pubmed/21320735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2011.01.003 |
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