Changes in Aromatase (CYP19) Gene Promoter Usage in Non-Small Cell Lung Cancer

In humans, aromatase (CYP19) gene expression is regulated via alternative promoters. Activation of each promoter gives rise to a CYP19 mRNA species with a unique 5′-untranslated region. Inhibition of aromatase has been reported to downregulate lung tumor growth. The genetic basis for CYP19 gene expr...

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Bibliografiset tiedot
Päätekijät: Demura, Masashi, Demura, Yoshiki, Ameshima, Shingo, Ishizaki, Takeshi, Sasaki, Masato, Miyamori, Isamu, Yamagishi, Masakazu, Takeda, Yoshiyu, Bulun, Serdar E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118270/
https://ncbi.nlm.nih.gov/pubmed/21320735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2011.01.003
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