The activation of nitric oxide synthase by copper ion is mediated by intracellular Ca(2+) mobilization in human pulmonary arterial endothelial cells

1. The aim of the study was to elucidate the vasodilatory mechanism due to Cu(2+) by assessing nitric oxide (NO) production as determined by NOx (NO, NO(2)(−), and NO(3)(−)) that is released from human pulmonary arterial endothelial cell (HPAEC) monolayers using a NO chemiluminescence analyzer, and...

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Bibliografiske detaljer
Main Authors: Demura, Yoshiki, Ishizaki, Takeshi, Ameshima, Shingo, Okamura, Seitarou, Hayashi, Takio, Matsukawa, Shigeru, Miyamori, Isamu
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565704/
https://ncbi.nlm.nih.gov/pubmed/9863645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702197
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