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Autophagy and p62/sequestosome 1 generate neo-antimicrobial peptides (cryptides) from cytosolic proteins

In a manifestation of the immunological autophagy termed xenophagy, autophagic adapter proteins such as p62 and NDP52 directly capture microbes for delivery to autophagosomal organelles where they are eliminated. In a mirror image phenomenon, which is also an immunological variant of the process ter...

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Autors principals: Ponpuak, Marisa, Deretic, Vojo
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359478/
https://ncbi.nlm.nih.gov/pubmed/21187720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.3.14500
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