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Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy
Polymorphisms in the IRGM gene, associated with Crohn disease (CD) and tuberculosis, are among the earliest identified examples documenting the role of autophagy in human disease. Functional studies have shown that IRGM protects against these diseases by modulating autophagy, yet the exact molecular...
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| I publikationen: | Autophagy |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835981/ https://ncbi.nlm.nih.gov/pubmed/26313894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1084457 |
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