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Delivery of Cytosolic Components by Autophagic Adapter Protein p62 Endows Autophagosomes with Unique Anti-Microbial Properties

Autophagy allows cells to self-digest portions of their own cytoplasm for a multitude of physiological purposes including innate and adaptive immunity functions. In one of its innate immunity manifestations, autophagy is known to contribute to the killing of intracellular microbes including Mycobact...

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Detalhes bibliográficos
Main Authors: Ponpuak, Marisa, Davis, Alexander S., Roberts, Esteban A., Delgado, Monica A., Dinkins, Christina, Zhao, Zijiang, Virgin, Herbert W., Kyei, George B., Johansen, Terje, Vergne, Isabelle, Deretic, Vojo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846977/
https://ncbi.nlm.nih.gov/pubmed/20206555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.02.009
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