PHARMACOLOGIC DOSES OF ASCORBIC ACID REPRESS SPECIFICITY PROTEIN (Sp) TRANSCRIPTION FACTORS AND Sp-REGULATED GENES IN COLON CANCER CELLS

Ascorbic acid (vitamin C) inhibits cancer cell growth and there is a controversy regarding the cancer chemoprotective effects of pharmacologic doses of this compound which exhibits pro-oxidant activity. We hypothesized that the anticancer activity of pharmacologic doses of ascorbic acid (< 5 mM)...

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Hlavní autoři: Pathi, Satya S., Lei, Ping, Sreevalsan, Sandeep, Chadalapaka, Gayathri, Jutooru, Indira, Safe, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359146/
https://ncbi.nlm.nih.gov/pubmed/21919647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2011.605984
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