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1,1-Bis(3′-indolyl)-1-(p-bromophenyl)methane and Related Compounds Repress Survivin and Decrease γ-Radiation-Induced Survivin in Colon and Pancreatic Cancer Cells

1,1-Bis(3′-indolyl)-1-(p-bromophenyl)methane (DIM-C-pPhBr) and the 2,2′-dimethyl analog (2,2′-diMeDIM-C-pPhBr) inhibit proliferation and induce apoptosis in SW480 colon and Panc28 pancreatic cancer cells. In this study, treatment with 10–20 μM concentrations of these compounds for 24 hr induced clea...

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Detalhes bibliográficos
Main Authors: Sreevalsan, Sandeep, Jutooru, Indira, Chadalapaka, Gayathri, Walker, Michael, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844344/
https://ncbi.nlm.nih.gov/pubmed/19787275
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