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1,1-Bis(3′-indolyl)-1-(p-bromophenyl)methane and Related Compounds Repress Survivin and Decrease γ-Radiation-Induced Survivin in Colon and Pancreatic Cancer Cells
1,1-Bis(3′-indolyl)-1-(p-bromophenyl)methane (DIM-C-pPhBr) and the 2,2′-dimethyl analog (2,2′-diMeDIM-C-pPhBr) inhibit proliferation and induce apoptosis in SW480 colon and Panc28 pancreatic cancer cells. In this study, treatment with 10–20 μM concentrations of these compounds for 24 hr induced clea...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2844344/ https://ncbi.nlm.nih.gov/pubmed/19787275 |
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