HMG–CoA Reductase Activation and Urinary Pellet Cholesterol Elevations in Acute Kidney Injury

SUMMARY: BACKGROUND AND OBJECTIVES: Experimental acute kidney injury (AKI) activates the HMG–CoA reductase (HMGCR) gene, producing proximal tubule cholesterol loading. AKI also causes sloughing of proximal tubular cell debris into tubular lumina. This study tested whether these two processes culmina...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Johnson, Ali CM, Ware, Lorraine B., Himmelfarb, Jonathan, Zager, Richard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Nephrology 2011
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359009/
https://ncbi.nlm.nih.gov/pubmed/21799150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.02440311
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