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Renal Ischemia-Induced Cholesterol Loading : Transcription Factor Recruitment and Chromatin Remodeling along the HMG CoA Reductase Gene
Acute kidney injury evokes renal tubular cholesterol synthesis. However, the factors during acute kidney injury that regulate HMG CoA reductase (HMGCR) activity, the rate-limiting step in cholesterol synthesis, have not been defined. To investigate these factors, mice were subjected to 30 minutes of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631318/ https://ncbi.nlm.nih.gov/pubmed/19095962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080602 |
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