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Renal Ischemia-Induced Cholesterol Loading : Transcription Factor Recruitment and Chromatin Remodeling along the HMG CoA Reductase Gene

Acute kidney injury evokes renal tubular cholesterol synthesis. However, the factors during acute kidney injury that regulate HMG CoA reductase (HMGCR) activity, the rate-limiting step in cholesterol synthesis, have not been defined. To investigate these factors, mice were subjected to 30 minutes of...

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Detalhes bibliográficos
Main Authors: Naito, Masayo, Bomsztyk, Karol, Zager, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631318/
https://ncbi.nlm.nih.gov/pubmed/19095962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080602
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