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Sphingolipids and cellular cholesterol homeostasis. Effect of ceramide on cholesterol trafficking and HMG CoA reductase activity

We previously showed that degradation of cellular sphingomyelin (SM) by SMase C results in a greater stimulation of cholesterol translocation to endoplasmic reticulum, compared to its degradation by SMase D. Here we investigated the hypothesis that the effect of SMase C is partly due to the generati...

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Hlavní autoři: Subbaiah, Papasani V., Sowa, Jennifer M., Singh, Dev K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464457/
https://ncbi.nlm.nih.gov/pubmed/18395507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.03.019
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