Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice

Obesity triggers a low-grade systemic inflammation, which plays an important role in the development of obesity-associated metabolic diseases. In searching for links between lipid accumulation and chronic inflammation, we examined invariant natural killer T (iNKT) cells, a subset of T lymphocytes th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wu, Lan, Parekh, Vrajesh V., Gabriel, Curtis L., Bracy, Deanna P., Marks-Shulman, Pamela A., Tamboli, Robyn A., Kim, Sungjune, Mendez-Fernandez, Yanice V., Besra, Gurdyal S., Lomenick, Jefferson P., Williams, Brandon, Wasserman, David H., Van Kaer, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358828/
https://ncbi.nlm.nih.gov/pubmed/22493234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200498109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados