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Glycolipid ligands of invariant natural killer T cells as vaccine adjuvants

Invariant natural killer T (iNKT) cells are a unique subset of T lymphocytes that recognize glycolipid antigens in the context of the antigen-presenting molecule CD1d. Upon glycolipid antigen stimulation, iNKT cells rapidly produce copious amounts of immunomodulatory cytokines, leading to potent act...

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Bibliographic Details
Main Authors: Kim, Sungjune, Lalani, Saif, Parekh, Vrajesh V, Wu, Lan, Van Kaer, Luc
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680388/
https://ncbi.nlm.nih.gov/pubmed/19053208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14760584.7.10.1519
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