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Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice

Invariant NKT (iNKT) cells are innate-like lymphocytes that recognize glycolipid antigens in the context of the MHC class I–like antigen-presenting molecule CD1d. In vivo activation of mouse iNKT cells with the glycolipid α-galactosylceramide (α-GalCer) results in the acquisition of a hyporesponsive...

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Detalhes bibliográficos
Main Authors: Kim, Sungjune, Lalani, Saif, Parekh, Vrajesh V., Vincent, Tiffaney L., Wu, Lan, Van Kaer, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2350429/
https://ncbi.nlm.nih.gov/pubmed/18451996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33071
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