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Exploring purine N7 interactions via atomic mutagenesis: The group I ribozyme as a case study
Atomic mutagenesis has emerged as a powerful tool to unravel specific interactions in complex RNA molecules. An early extensive study of analogs of the exogenous guanosine nucleophile in group I intron self-splicing by Bass and Cech demonstrated structure–function relationships analogous to those se...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Cold Spring Harbor Laboratory Press
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358644/ https://ncbi.nlm.nih.gov/pubmed/22543863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.031567.111 |
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