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Involvement of Notch Signaling Pathway in Regulating IL-12 Expression via c-Rel in Activated Macrophages

Macrophages play an important role both in innate and adaptive immune responses. Treatment with interferon (IFN) γ together with lipopolysaccharide (LPS) activates pro-inflammatory macrophages which secrete various pro-inflammatory cytokines including IL-12. IL-12 promotes a Th1 type immune response...

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Bibliografske podrobnosti
Main Authors: Boonyatecha, Natt, Sangpetch, Naunpun, Wongchana, Wipawee, Kueanjinda, Pathipak, Palaga, Tanapat
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358353/
https://ncbi.nlm.nih.gov/pubmed/22463790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.03.017
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