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Involvement of Notch Signaling Pathway in Regulating IL-12 Expression via c-Rel in Activated Macrophages
Macrophages play an important role both in innate and adaptive immune responses. Treatment with interferon (IFN) γ together with lipopolysaccharide (LPS) activates pro-inflammatory macrophages which secrete various pro-inflammatory cytokines including IL-12. IL-12 promotes a Th1 type immune response...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3358353/ https://ncbi.nlm.nih.gov/pubmed/22463790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.03.017 |
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