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Impact of Notch1 Deletion in Macrophages on Pro-inflammatory Cytokine Production and the Outcome of Experimental Autoimmune Encephalomyelitis

Notch signaling is involved in regulating TLR-mediated responses in activated macrophages. In this study, we investigated the impact of Notch signaling in macrophages in an experimental autoimmune encephalomyelitis (EAE) model. To examine the impact of deficiency in Notch signaling in activated macr...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wongchana, Wipawee, Lawlor, Rebecca G., Osborne, Barbara A., Palaga, Tanapat
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691704/
https://ncbi.nlm.nih.gov/pubmed/26503951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401770
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