COP 9 Signalosome Subunit 6 Stabilizes COP1, which Functions as an E3 Ubiquitin Ligase for 14-3-3σ

14-3-3σ, a gene upregulated by p53 in response to DNA damage, exists as part of a positive-feedback loop which activates p53 and is a human cancer epithelial marker downregulated in various cancer types. 14-3-3σ levels are critical for maintaining p53 activity in response to DNA damage and regulatin...

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Библиографические подробности
Главные авторы: Choi, Hyun Ho, Gully, Christopher P., Su, Chun-Hui, Velazquez-Torres, Guermarie, Chou, Ping-Chieh, Tseng, Chieh, Zhao, Ruiying, Phan, Liem, Shaikenov, Tattym, Chen, Jian, Yeung, Sai-Ching J., Lee, Mong-Hong
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358116/
https://ncbi.nlm.nih.gov/pubmed/21625211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.192
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