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Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage
Mammalian constitutive photomorphogenic 1 (COP1) is a p53 E3 ubiquitin ligase involved in regulating p53 protein level. In plants, the dynamic cytoplasm/nucleus distribution of COP1 is important for its function in terms of catalyzing the degradation of target proteins. In mammalian cells, the biolo...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949799/ https://ncbi.nlm.nih.gov/pubmed/20843328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-243 |
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