Nuclear export regulation of COP1 by 14-3-3σ in response to DNA damage

Mammalian constitutive photomorphogenic 1 (COP1) is a p53 E3 ubiquitin ligase involved in regulating p53 protein level. In plants, the dynamic cytoplasm/nucleus distribution of COP1 is important for its function in terms of catalyzing the degradation of target proteins. In mammalian cells, the biolo...

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Bibliographische Detailangaben
Hauptverfasser: Su, Chun-Hui, Zhao, Ruiying, Velazquez-Torres, Guermarie, Chen, Jian, Gully, Christopher, Yeung, Sai-Ching J, Lee, Mong-Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949799/
https://ncbi.nlm.nih.gov/pubmed/20843328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-243
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