The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming

Extensive reprogramming of cellular energy metabolism is a hallmark of cancer. Despite its importance, the molecular mechanism controlling this tumour metabolic shift remains not fully understood. Here we show that 14-3-3σ regulates cancer metabolic reprogramming and protects cells from tumourigenic...

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Publicat a:Nat Commun
Autors principals: Phan, Liem, Chou, Ping-Chieh, Velazquez-Torres, Guermarie, Samudio, Ismael, Parreno, Kenneth, Huang, Yaling, Tseng, Chieh, Vu, Thuy, Gully, Chris, Su, Chun-Hui, Wang, Edward, Chen, Jian, Choi, Hyun-Ho, Fuentes-Mattei, Enrique, Shin, Ji-Hyun, Shiang, Christine, Grabiner, Brian, Blonska, Marzenna, Skerl, Stephen, Shao, Yiping, Cody, Dianna, Delacerda, Jorge, Kingsley, Charles, Webb, Douglas, Carlock, Colin, Zhou, Zhongguo, Hsieh, Yun-Chih, Lee, Jaehyuk, Elliott, Andrew, Ramirez, Marc, Bankson, Jim, Hazle, John, Wang, Yongxing, Li, Lei, Weng, Shaofan, Rizk, Nibal, Wen, Yu Ye, Lin, Xin, Wang, Hua, Wang, Huamin, Zhang, Aijun, Xia, Xuefeng, Wu, Yun, Habra, Mouhammed, Yang, Wei, Pusztai, Lajos, Yeung, Sai-Ching, Lee, Mong-Hong
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507299/
https://ncbi.nlm.nih.gov/pubmed/26179207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8530
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