CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-κB activation

G protein-coupled receptors (GPCRs) play pivotal roles in regulating various cellular functions. Although many GPCRs induce NF-κB activation, the molecular mechanism of GPCR-induced NF-κB activation remains largely unknown. CARMA3 (CARD and MAGUK domain-containing protein 3) is a scaffold molecule w...

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Detalhes bibliográficos
Main Authors: Grabiner, Brian C., Blonska, Marzenna, Lin, Pei-Chun, You, Yun, Wang, Donghai, Sun, Jiyuan, Darnay, Bryant G., Dong, Chen, Lin, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847715/
https://ncbi.nlm.nih.gov/pubmed/17438001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1502507
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