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CARMA3 is crucial for EGFR-induced activation of NF-κB and tumor progression
EGF activates NF-κB and constitutively activated NF-κB contributes to EGFR mutation-associated tumorigenesis, but it remains unclear precisely how EGFR signaling leads to NF-κB activation. Here we report that CARMA3, a Caspase Recruitment Domain (CARD)-containing scaffold molecule, is required for E...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3059846/ https://ncbi.nlm.nih.gov/pubmed/21406399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3626 |
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