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Beyond NF-κB activation: nuclear functions of IκB kinase α

IκB kinase (IKK) complex, the master kinase for NF-κB activation, contains two kinase subunits, IKKα and IKKβ. In addition to mediating NF-κB signaling by phosphorylating IκB proteins during inflammatory and immune responses, the activation of the IKK complex also responds to various stimuli to regu...

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Détails bibliographiques
Auteurs principaux: Huang, Wei-Chien, Hung, Mien-Chie
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563485/
https://ncbi.nlm.nih.gov/pubmed/23343355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-3
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