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Phosphorylation of CBP by IKKα Promotes Cell Growth by Switching the Binding Preference of CBP from p53 to NF-κB

CBP plays a central role in coordinating and integrating multiple signaling pathways. Competition between NF-κB and p53 for CBP is a crucial determinant of whether a cell proliferates or undergoes apoptosis. However, how the CBP-dependent cross-talk between these two transcription factors is regulat...

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Detalhes bibliográficos
Main Authors: Huang, Wei-Chien, Ju, Tsai-Kai, Hung, Mien-Chie, Chen, Ching-Chow
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2312502/
https://ncbi.nlm.nih.gov/pubmed/17434128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.02.019
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