Evaluation of Allele-Specific Somatic Changes of Genome-Wide Association Study Susceptibility Alleles in Human Colorectal Cancers

BACKGROUND: Tumors frequently exhibit loss of tumor suppressor genes or allelic gains of activated oncogenes. A significant proportion of cancer susceptibility loci in the mouse show somatic losses or gains consistent with the presence of a tumor susceptibility or resistance allele. Thus, allele-spe...

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Detalhes bibliográficos
Main Authors: Gerber, Madelyn M., Hampel, Heather, Schulz, Nathan P., Fernandez, Soledad, Wei, Lai, Zhou, Xiao-Ping, de la Chapelle, Albert, Toland, Amanda Ewart
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357346/
https://ncbi.nlm.nih.gov/pubmed/22629442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037672
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