Recycling Between Cortisol and Cortisone in Human Splanchnic, Subcutaneous Adipose, and Skeletal Muscle Tissues In Vivo

11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome because it catalyses reductase regeneration of cortisol from cortisone in adipose and liver. 11βHSD1 can also catalyze the reverse dehydrogenase reaction in vitro (e.g., if cofactor is limited). We used s...

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Detalhes bibliográficos
Main Authors: Hughes, Katherine A., Manolopoulos, Konstantinos N., Iqbal, Javaid, Cruden, Nicholas L., Stimson, Roland H., Reynolds, Rebecca M., Newby, David E., Andrew, Ruth, Karpe, Fredrik, Walker, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Methodology Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357308/
https://ncbi.nlm.nih.gov/pubmed/22511204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1345
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