Recycling Between Cortisol and Cortisone in Human Splanchnic, Subcutaneous Adipose, and Skeletal Muscle Tissues In Vivo

11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome because it catalyses reductase regeneration of cortisol from cortisone in adipose and liver. 11βHSD1 can also catalyze the reverse dehydrogenase reaction in vitro (e.g., if cofactor is limited). We used s...

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Détails bibliographiques
Auteurs principaux: Hughes, Katherine A., Manolopoulos, Konstantinos N., Iqbal, Javaid, Cruden, Nicholas L., Stimson, Roland H., Reynolds, Rebecca M., Newby, David E., Andrew, Ruth, Karpe, Fredrik, Walker, Brian R.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2012
Sujets:
Methodology Review
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357308/
https://ncbi.nlm.nih.gov/pubmed/22511204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1345
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