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Displacement of Cortisol From Human Heart by Acute Administration of a Mineralocorticoid Receptor Antagonist
CONTEXT: Mineralocorticoid receptor (MR) antagonists have beneficial effects in patients with heart failure and myocardial infarction, often attributed to blocking aldosterone action in the myocardium. However, binding of aldosterone to MR requires local activity of the enzyme 11β-hydroxysteroid deh...
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| Publicado no: | J Clin Endocrinol Metab |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392799/ https://ncbi.nlm.nih.gov/pubmed/24423282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-2049 |
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