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Mineralocorticoid Receptor Antagonists for Treatment of Hypertension and Heart Failure

Spironolactone and eplerenone are both mineralocorticoid-receptor antagonists. These compounds block both the epithelial and nonepithelial actions of aldosterone, with the latter assuming increasing clinical relevance. Spironolactone and eplerenone both affect reductions in blood pressure either as...

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Pubblicato in:Methodist Debakey Cardiovasc J
Autore principale: Sica, Domenic A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Methodist Hospital Houston, Texas 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814010/
https://ncbi.nlm.nih.gov/pubmed/27057293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14797/mdcj-11-4-235
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