The Novel Therapeutic Effect of Phosphoinositide 3-Kinase-γ Inhibitor AS605240 in Autoimmune Diabetes

Type 1 diabetes (T1D) remains a major health problem worldwide, with a steadily rising incidence yet no cure. Phosphoinositide 3-kinase-γ (PI3Kγ), a member of a family of lipid kinases expressed primarily in leukocytes, has been the subject of substantial research for its role in inflammatory diseas...

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Hlavní autoři: Azzi, Jamil, Moore, Robert F., Elyaman, Wassim, Mounayar, Marwan, El Haddad, Najib, Yang, Sunmi, Jurewicz, Mollie, Takakura, Ayumi, Petrelli, Alessandra, Fiorina, Paolo, Ruckle, Thomas, Abdi, Reza
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2012
Témata:
Immunology and Transplantation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357271/
https://ncbi.nlm.nih.gov/pubmed/22403300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0134
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