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The role of HCA2 (GPR109A) in regulating macrophage function

We investigated the novel role of HCA2 (GPR109A) and its ligand nicotinic acid in regulating macrophage function. Hca2 expression in the RAW264.7 murine macrophage cell line is strongly induced by LPS treatment and correlates with the expression of TNF-α. Treatment with 300 μM nicotinic acid (report...

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Detalhes bibliográficos
Main Authors: Zandi-Nejad, Kambiz, Takakura, Ayumi, Jurewicz, Mollie, Chandraker, Anil K., Offermanns, Stefan, Mount, David, Abdi, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804742/
https://ncbi.nlm.nih.gov/pubmed/23882124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-223933
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