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Endogenous Modulators and Pharmacological Inhibitors of Histone Deacetylases in Cancer Therapy
The class I histone deacetylases HDAC1 and HDAC2 belong to a family of 11 zinc-dependent human HDACs and are overexpressed in many cancers. Inhibitors of these HDACs now in clinical trials show activity against several types of cancers. This review is focuse on recent advances in both clinical and p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3356932/ https://ncbi.nlm.nih.gov/pubmed/21725353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.267 |
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