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Histone Deacetylase Inhibitor Therapy in Epithelial Ovarian Cancer

Since epigenetic alterations are believed to be involved in the repression of tumor suppressor genes and promotion of tumorigenesis in ovarian cancers, novel compounds endowed with a histone deacetylase (HDAC) inhibitory activity are an attractive therapeutic approach. In this review, we discuss the...

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Detalhes bibliográficos
Main Authors: Takai, Noriyuki, Narahara, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801002/
https://ncbi.nlm.nih.gov/pubmed/20052384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/458431
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